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“The initiation of our Phase IIb trial with tezampanel is an acute milestone for TorreyPines and a promising development for the millions of folks who suffer with acute migraine,” said Neil Kurtz, M.D., President and Chief Executive Officer of TorreyPines. “We propose that tezampanel will not singular release the acute pain associated with migraine, but also address the underlying piece of kit that precipitate the migraine. Tezampanel particular the forthcoming to proposition an important unusual mechanism of accomplishment to the treatment of migraine.” In former clinical trial, tezampanel has be administered to farther than 200 war fit fully developed volunteers or patients. In five Phase IIa, placebo-controlled trials, tezampanel demonstrated verification of hypothesis in multiple pain quintessence. In a placebo and active-controlled trial in patients with acute migraine, the compound, administered intravenously, achieve statistical weightiness in all primary and minor endpoints traditionally sought after for regulatory confirmation. These endpoints integrated pain relief at two hours, pain-free at two hours and relief of nausea, photophobia and phonophobia.

These and other personage factors are discuss in greater refinement in Aastrom’s Annual Report on Form 10-K and other filings with the Securities and Exchange Commission.