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NASONEX(R) Now FDA-Approved in USA for Nasal Polyps

February 5th, 2009 · No Comments
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“The repeat the praise of of NASONEX for the treatment of nasal polyps provide patients near a locked and moody first-line treatment that deliver pills head-on to the challenge measurement,” said Robert J. Spiegel, M.D., chief medical officer and mastermind vice president, Schering-Plough. “NASONEX, previously own once or twofold on a daily basis, reduce nasal polyps and relieve symptom, together with congestion.” The foreign witness for NASONEX be base on top of background submit from two controlled suffering involving 664 patients 18 to 86 years of age. Patients received any NASONEX 200 mcg once daily, NASONEX 200 mcg twice daily or a placebo. In the first den, a statistically weighty let-up in polyp order be observed at the four-month endpoint in patients reception NASONEX 200 mcg either once or twice daily, compare to the placebo splinter group. In the second study, patients receiving NASONEX twice daily demonstrated significant reduction of polyp grade compared to the placebo group, and patients receiving once-daily regime demonstrated a numerical but not significant reduction in polyp grade. Both study show a statistically significant reduction in congestion for both dose versus the placebo group. Based on the data, the approved indication recommend a 200 mcg dose given twice-daily. A dose of 200 mcg once-daily also is effective in one patients.

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